Cynthia Green, PhD

Department:
Biostatistics and Bioinformatics

Email Address:
cindy.green@duke.edu

Address:
Box 3850
DUMC
Durham, NC 27710

Telephone:
9196688853

Fax Telephone:
9196687058

Research Interests:
Survival Analysis
Longitudinal Data Analysis
Logistic Regression
Missing Data
Clinical Trial Methods
Maximum Likelihood Methods

Publications:
2009 -- Pubmed # 19474784 -- Whellan DJ, Green CL, Piccini JP, Krucoff MW. QT as a safety biomarker in drug development. Clin Pharmacol Ther. 2009 Jul;86(1):101-4.

2005 -- Pubmed # 15721101 -- Rebeiz AG, Johanson P, Green CL, Crater SW, Roe MT, Langer A, Giugliano RP, Lincoff AM, Newby LK, Harrington RA, Topol EJ, Califf RM, Wagner GS, Krucoff MW. Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials). Am J Cardiol. 2005 Mar 1;95(5):611-4.

2004 -- Pubmed # 15131541 -- Gibson CM, Karha J, Giugliano RP, Roe MT, Murphy SA, Harrington RA, Green CL, Schweiger MJ, Miklin JS, Baran KW, Palmeri S, Braunwald E, Krucoff MW, . Association of the timing of ST-segment resolution with TIMI myocardial perfusion grade in acute myocardial infarction. Am Heart J. 2004 May;147(5):847-52.

2004 -- Pubmed # 15077087 -- Maas AC, Wyatt CM, Green CL, Wagner GS, Trollinger KM, Pope JE, Langer A, Armstrong PW, Califf RM, Simoons ML, Krucoff MW. Combining baseline clinical descriptors and real-time response to therapy: the incremental prognostic value of continuous ST-segment monitoring in acute myocardial infarction. Am Heart J. 2004 Apr;147(4):698-704.

2004 -- Pubmed # 15589009 -- Nelwan SP, Crater SW, Green CL, Johanson P, van Dam TB, Meij SH, Simoons ML, Krucoff MW. Assessment of derived 12-lead electrocardiograms using general and patient-specific reconstruction strategies at rest and during transient myocardial ischemia. Am J Cardiol. 2004 Dec 15;94(12):1529-33.

2004 -- Pubmed # 14975462 -- Roe MT, Green CL, Giugliano RP, Gibson CM, Baran K, Greenberg M, Palmeri ST, Crater S, Trollinger K, Hannan K, Harrington RA, Krucoff MW, . Improved speed and stability of ST-segment recovery with reduced-dose tenecteplase and eptifibatide compared with full-dose tenecteplase for acute ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2004 Feb 18;43(4):549-56.

2003 -- Pubmed # 14609586 -- Engelen DJ, Gressin V, Krucoff MW, Theuns DA, Green C, Cheriex EC, Maison-Blanche P, Dassen WR, Wellens HJ, Gorgels AP. Usefulness of frequent arrhythmias after epicardial recanalization in anterior wall acute myocardial infarction as a marker of cellular injury leading to poor recovery of left ventricular function. Am J Cardiol. 2003 Nov 15;92(10):1143-9.

2003 -- Pubmed # 14580299 -- Grunberg GE, Crater SW, Green CL, Seskevich J, Lane JD, Koenig HG, Bashore TM, Morris KG, Mark DB, Krucoff MW. Correlations between preprocedure mood and clinical outcome in patients undergoing coronary angioplasty. Cardiol Rev. 2003 Nov-Dec;11(6):309-17.

2003 -- Pubmed # 12972102 -- Kandzari DE, Labinaz M, Cantor WJ, Madan M, Gallup DS, Hasselblad V, Joseph D, Allen A, Green C, Hidinger KG, Krucoff MW, Christenson RH, Harrington RA, Tcheng JE. Reduction of myocardial ischemic injury following coronary intervention (the MC-1 to Eliminate Necrosis and Damage trial). Am J Cardiol. 2003 Sep 15;92(6):660-4.

2001 -- Pubmed # 11685160 -- Krucoff MW, Crater SW, Green CL, Maas AC, Seskevich JE, Lane JD, Loeffler KA, Morris K, Bashore TM, Koenig HG. Integrative noetic therapies as adjuncts to percutaneous intervention during unstable coronary syndromes: Monitoring and Actualization of Noetic Training (MANTRA) feasibility pilot. Am Heart J. 2001 Nov;142(5):760-9.

2000 -- Pubmed # 10801752 -- Andrews J, Straznicky IT, French JK, Green CL, Maas AC, Lund M, Krucoff MW, White HD. ST-Segment recovery adds to the assessment of TIMI 2 and 3 flow in predicting infarct wall motion after thrombolytic therapy. Circulation. 2000 May 9;101(18):2138-43.

2000 -- Pubmed # 10818328 -- Lubarsky DA, Fisher SD, Slaughter TF, Green CL, Lineberger CK, Astles JR, Greenberg CS, Inge WW 3rd, Krucoff MW. Myocardial ischemia correlates with reduced fibrinolytic activity following peripheral vascular surgery. J Clin Anesth. 2000 Mar;12(2):136-41.

2000 -- Pubmed # 10716469 -- Shah A, Wagner GS, Granger CB, O'Connor CM, Green CL, Trollinger KM, Califf RM, Krucoff MW. Prognostic implications of TIMI flow grade in the infarct related artery compared with continuous 12-lead ST-segment resolution analysis. Reexamining the "gold standard" for myocardial reperfusion assessment. J Am Coll Cardiol. 2000 Mar 1;35(3):666-72.

1999 -- Pubmed # 10080417 -- Blankenship JC, Krucoff MW, Werns SW, Anderson HV, Landau C, White HJ, Green CL, Spokojny AM, Bach RG, Raymond RE, Pinkston J, Rawert M, Talley JD. Comparison of slow oscillating versus fast balloon inflation strategies for coronary angioplasty. Am J Cardiol. 1999 Mar 1;83(5):675-80.

1999 -- Pubmed # 10467200 -- Mahaffey KW, Granger CB, Sloan MA, Green CL, Gore JM, Weaver WD, White HD, Simoons ML, Barbash GI, Topol EJ, Califf RM. Neurosurgical evacuation of intracranial hemorrhage after thrombolytic therapy for acute myocardial infarction: experience from the GUSTO-I trial. Global Utilization of Streptokinase and tissue-plasminogen activator (tPA) for Occluded Coronary Arteries. Am Heart J. 1999 Sep;138(3 Pt 1):493-9.

1998 -- Pubmed # 9535493 -- Fisher SD, Loeffler AK, Green CL, Wildermann NM, Pope JE, Krucoff MW. Device implementation, validation, and application assessment of two continuous 12-lead ECG monitors during percutaneous transluminal coronary angioplasty: description of the validation method and implications for clinical trials. J Electrocardiol. 1998;30 Suppl:149-54.

1998 -- Pubmed # 9506593 -- Gebel JM, Sila CA, Sloan MA, Granger CB, Mahaffey KW, Weisenberger J, Green CL, White HD, Gore JM, Weaver WD, Califf RM, Topol EJ. Thrombolysis-related intracranial hemorrhage: a radiographic analysis of 244 cases from the GUSTO-1 trial with clinical correlation. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. Stroke. 1998 Mar;29(3):563-9.

1998 -- Pubmed # 9731597 -- Gebel JM, Sila CA, Sloan MA, Granger CB, Weisenberger JP, Green CL, Topol EJ, Mahaffey KW. Comparison of the ABC/2 estimation technique to computer-assisted volumetric analysis of intraparenchymal and subdural hematomas complicating the GUSTO-1 trial. Stroke. 1998 Sep;29(9):1799-801.

1998 -- Pubmed # 9576155 -- Pracyk JB, Wall TC, Longabaugh JP, Tice FD, Hochrein J, Green C, Cox G, Lee K, Stack RS, Tcheng JE. A randomized trial of vascular hemostasis techniques to reduce femoral vascular complications after coronary intervention. Am J Cardiol. 1998 Apr 15;81(8):970-6.

1998 -- Pubmed # 9760291 -- Sloan MA, Sila CA, Mahaffey KW, Granger CB, Longstreth WT Jr, Koudstaal P, White HD, Gore JM, Simoons ML, Weaver WD, Green CL, Topol EJ, Califf RM. Prediction of 30-day mortality among patients with thrombolysis-related intracranial hemorrhage. Circulation. 1998 Oct 6;98(14):1376-82.

1997 -- Pubmed # 9362405 -- Shah A, Wagner GS, Califf RM, Boineau RE, Green CL, Wildermann NM, Trollinger KM, Pope JE, Krucoff MW. Comparative prognostic significance of simultaneous versus independent resolution of ST segment depression relative to ST segment elevation during acute myocardial infarction. J Am Coll Cardiol. 1997 Nov 15;30(6):1478-83.

1997 -- Pubmed # 9285669 -- Shah A, Wagner GS, Green CL, Crater SW, Sawchak ST, Wildermann NM, Mark DB, Waugh RA, Krucoff MW. Electrocardiographic differentiation of the ST-segment depression of acute myocardial injury due to the left circumflex artery occlusion from that of myocardial ischemia of nonocclusive etiologies. Am J Cardiol. 1997 Aug 15;80(4):512-3.

1997 -- Pubmed # 9014973 -- Tardiff BE, Califf RM, Morris D, Bates E, Woodlief LH, Lee KL, Green C, Rutsch W, Betriu A, Aylward PE, Topol EJ. Coronary revascularization surgery after myocardial infarction: impact of bypass surgery on survival after thrombolysis. GUSTO Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. J Am Coll Cardiol. 1997 Feb;29(2):240-9.

1996 -- Pubmed # 8737099 -- Klootwijk P, Langer A, Meij S, Green C, Veldkamp RF, Ross AM, Armstrong PW, Simoons ML. Non-invasive prediction of reperfusion and coronary artery patency by continuous ST segment monitoring in the GUSTO-I trial. Eur Heart J. 1996 May;17(5):689-98.

1996 -- Pubmed # 8921783 -- Newby KH, Pisanó E, Krucoff MW, Green C, Natale A. Incidence and clinical relevance of the occurrence of bundle-branch block in patients treated with thrombolytic therapy. Circulation. 1996 Nov 15;94(10):2424-8.

1995 -- Pubmed # 7895349 -- Granger CB, Miller JM, Bovill EG, Gruber A, Tracy RP, Krucoff MW, Green C, Berrios E, Harrington RA, Ohman EM. Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes. Circulation. 1995 Apr 1;91(7):1929-35.

1994 -- Pubmed # 7884367 -- Krucoff MW, Green CL, Harrell FE, Simoons ML, Wilderman NM, Trollinger KM, Sawchak ST, Pope JE, Shah A, Granger CB. From signal/noise to information content/noise. Reconsidering the statistical analysis of continuous ST-segment data streams with gaps: potential optimization of application-specific information content using left, right, and interval censoring. J Electrocardiol. 1994;27 Suppl:233-7.

1994 -- Pubmed # 7884371 -- Shah A, Green CL, Trollinger KM, Wilderman NM, Pope JE, Califf RM, Wagner GS, Krucoff MW. Reassessing the clinical significance of ST-segment depression that occurs concomitantly with the ST-segment elevation during acute myocardial infarction with the use of continuous ST-segment analysis. J Electrocardiol. 1994;27 Suppl:256-9.

1994 -- Pubmed # 8198032 -- Veldkamp RF, Green CL, Wilkins ML, Pope JE, Sawchak ST, Ryan JA, Califf RM, Wagner GS, Krucoff MW. Comparison of continuous ST-segment recovery analysis with methods using static electrocardiograms for noninvasive patency assessment during acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 7 Study Group. Am J Cardiol. 1994 Jun 1;73(15):1069-74.

1993 -- Pubmed # 8189133 -- Krucoff MW, Green CL, Langer A, Klootwijk LJ, Trollinger KM, Sawchak ST, Wilderman NM, Veldkamp RF, Pope JE, Simoons ML. Global utilization of streptokinase and tPA for occluded arteries (GUSTO) ECG-monitoring substudy. Study design and technical considerations. J Electrocardiol. 1993;26 Suppl:249-55.

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