Min Lin, PhD

Department:
Biostatistics and Bioinformatics

Email Address:
annie.lin@duke.edu

Website:
crtp.mc.duke.edu/faculty_detail.asp?id=lin00044&type=bio

Address:
DUMC Box 2721

Durham, NC 27710

Telephone:
9196684602

Fax Telephone:
9196687049

Research Interests:
Methodology development in statistical genetics; design and analysis of clinical trials; pharmacogenomics and pharmacogenetics.

Publications:
2006 -- Lin M, Wu R, Johnson JA. A Bivariate Functional Mapping Model for Identifying Haplotypes that Control Drug Response for Systolic and Diastolic Blood Pressures. Pac Symp Biocomput. 2006;: 572-583.

2006 -- Pubmed # 16539724 -- Lin M, Wu R. A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event. BMC Bioinformatics. 2006 Mar 15;7(1):138.

2006 -- Lin M, Wu R. Detecting sequence-sequence interactions for complex diseases. Current Genomics, 2006; 7: 59-72.

2006 -- Pubmed # 16485021 -- Wu R, Lin M. Functional mapping - how to map and study the genetic architecture of dynamic complex traits. Nat Rev Genet. 2006 Mar;7(3):229-37.

2005 -- Pubmed # 15782224 -- Lin M, Aquilante C, Johnson JA, Wu R. Sequencing drug response with HapMap. Pharmacogenomics J. 2005;5(3):149-56.

2005 -- Pubmed # 16180591 -- Lin M, Ma CX, Zhao W, Cheverud JM, Wu R. Mechanistic mapping of ontogenetic growth based on biological principles. Growth Dev Aging. 2005;69(1):31-7.

2005 -- Pubmed # 15802521 -- Lin M, Wu R. Theoretical basis for the identification of allelic variants that encode drug efficacy and toxicity. Genetics. 2005 Jun;170(2):919-28.

2004 -- Pubmed # 14586505 -- Ma CX, Lin M, Littell RC, Yin T, Wu R. A likelihood approach for mapping growth trajectories using dominant markers in a phase-unknown full-sib family. Theor Appl Genet. 2004 Feb;108(4):699-705.

2004 -- Pubmed # 15082567 -- Wu R, Ma CX, Lin M, Casella G. A general framework for analyzing the genetic architecture of developmental characteristics. Genetics. 2004 Mar;166(3):1541-51.

2004 -- Pubmed # 15339296 -- Wu R, Ma CX, Lin M, Wang Z, Casella G. Functional mapping of quantitative trait loci underlying growth trajectories using a transform-both-sides logistic model. Biometrics. 2004 Sep;60(3):729-38.

2003 -- Pubmed # 14573497 -- Lin M, Lou XY, Chang M, Wu R. A general statistical framework for mapping quantitative trait loci in nonmodel systems: issue for characterizing linkage phases. Genetics. 2003 Oct;165(2):901-13.

2003 -- Pubmed # 12925888 -- Lou XY, Todhunter RJ, Lin M, Lu Q, Liu T, Wang Z, Bliss SP, Casella G, Acland GM, Lust G, Wu R. The extent and distribution of linkage disequilibrium in a multi-hierarchic outbred canine pedigree. Mamm Genome. 2003 Aug;14(8):555-64.