Yuliya Lokhnygina, PhD

Department:
Biostatistics and Bioinformatics

Email Address:
lokhn001@notes.duke.edu

Address:
Box 3850
DUMC
Durham, NC 27710

Telephone:
9196687814

Research Interests:
Statistical methods in clinical trials, survival analysis, adaptive designs, adaptive treatment strategies, causal inference in observational studies, semiparametric inference

Publications:
2009 -- Pubmed # 19576338 -- Califf RM, Lokhnygina Y, Velazquez EJ, McMurray JJ, Leimberger JD, Lewis EF, Diaz R, Murin J, Pfeffer MA. Usefulness of beta blockers in high-risk patients after myocardial infarction in conjunction with captopril and/or valsartan (from the VALsartan In Acute Myocardial Infarction [VALIANT] trial). Am J Cardiol. 2009 Jul 15;104(2):151-7.

2009 -- Pubmed # 19477496 -- Hofmann AM, Scurlock AM, Jones SM, Palmer KP, Lokhnygina Y, Steele PH, Kamilaris J, Burks AW. Safety of a peanut oral immunotherapy protocol in children with peanut allergy. J Allergy Clin Immunol. 2009 Aug;124(2):286-291.e6.

2009 -- Pubmed # 19463409 -- Kandzari DE, Rao SV, Moses JW, Dzavik V, Strauss BH, Kutryk MJ, Simonton CA, Garg J, Lokhnygina Y, Mancini GB, Yeoh E, Buller CE, . Clinical and angiographic outcomes with sirolimus-eluting stents in total coronary occlusions: the ACROSS/TOSCA-4 (Approaches to Chronic Occlusions With Sirolimus-Eluting Stents/Total Occlusion Study of Coronary Arteries-4) trial. JACC Cardiovasc Interv. 2009 Feb;2(2):97-106.

2008 -- Lokhnygina Y, Tsiatis AA Optimal two-stage group-sequential designs. Journal of Statistical Planning and Inference 2008; 138(2): 489-99


2008 -- Pubmed # 18082495 -- Thomas KL, Al-Khatib SM, Lokhnygina Y, Solomon SD, Kober L, McMurray JJ, Califf RM, Velazquez EJ. Amiodarone use after acute myocardial infarction complicated by heart failure and/or left ventricular dysfunction may be associated with excess mortality. Am Heart J. 2008 Jan;155(1):87-93.

2007 -- Pubmed # 17613650 -- Barnhart HX, Lokhnygina Y, Kosinski AS, Haber M. Comparison of concordance correlation coefficient and coefficient of individual agreement in assessing agreement. J Biopharm Stat. 2007;17(4):721-38.

2007 -- Pubmed # 17719273 -- Hasselblad V, Gattis Stough W, Shah MR, Lokhnygina Y, O'Connor CM, Califf RM, Adams KF Jr. Relation between dose of loop diuretics and outcomes in a heart failure population: results of the ESCAPE trial. Eur J Heart Fail. 2007 Oct;9(10):1064-9.

2007 -- Hasselblad V, Lokhnygina Y, Krucoff MW. Discussion of: Statistical and Regulatory Issues with the Application of Propensity Score Analysis to Nonrandomized Medical Device Clinical Studies. J of Biopharm Stat 2007;17(1):19-21


2007 -- Pubmed # 17425633 -- Lokhnygina Y, Helterbrand JD. Cox regression methods for two-stage randomization designs. Biometrics. 2007 Jun;63(2):422-8.

2007 -- Pubmed # 17880325 -- Mehta RH, Greenbaum AB, Lokhnygina Y, Newby LK, Van De Werf F, Armstrong PW, Pieper KS, Califf RM, Granger CB, Harrington RA. Timing of death and myocardial infarction in patients with non-ST elevation acute coronary syndromes: insights from randomized clinical trials. J Interv Cardiol. 2007 Oct;20(5):299-306.

2007 -- Pubmed # 17218552 -- Niewoehner DE, Lokhnygina Y, Rice K, Kuschner WG, Sharafkhaneh A, Sarosi GA, Krumpe P, Pieper K, Kesten S. Risk indexes for exacerbations and hospitalizations due to COPD. Chest. 2007 Jan;131(1):20-8.

2007 -- Pubmed # 16984929 -- Sampson UK, Pfeffer MA, McMurray JJ, Lokhnygina Y, White HD, Solomon SD, . Predictors of stroke in high-risk patients after acute myocardial infarction: insights from the VALIANT Trial. Eur Heart J. 2007 Mar;28(6):685-91.

2007 -- Pubmed # 18025532 -- Tricoci P, Lokhnygina Y, Berdan LG, Steinhubl SR, Gulba DC, White HD, Kleiman NS, Aylward PE, Langer A, Califf RM, Ferguson JJ, Antman EM, Newby LK, Harrington RA, Goodman SG, Mahaffey KW. Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial. Circulation. 2007 Dec 4;116(23):2669-77.

2006 -- Pubmed # 17161049 -- White HD, Kleiman NS, Mahaffey KW, Lokhnygina Y, Pieper KS, Chiswell K, Cohen M, Harrington RA, Chew DP, Petersen JL, Berdan LG, Aylward PE, Nessel CC, Ferguson JJ 3rd, Califf RM. Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial. Am Heart J. 2006 Dec;152(6):1042-50.