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Michael Pencina Leads Study that Finds New Guidelines May Double Statin Use

March 31, 2014

Michael Pencina led an analysis published in the New England Journal of Medicine that found almost half of Americans ages 40 to 75 and nearly all men over 60 qualify to consider cholesterol-lowering statin drugs under new heart disease prevention guidelines.  "The numbers tell a story about how much heart diseasewe still have in the U.S.," Pencina said.  "In fairness they are just guidelines to start the conversation."  This study was carried by newspapers and online news sites nationwide.  The full AP article here.
 

Duke Offers Ph.D. in Biostatistics

Building on its successful Master of Biostatistics Program, the Department of Biostatistics and Bioinformatics is offering a Ph.D. in Biostatistics through the Graduate School of Duke University. As with the master’s program, the Ph.D. program will emphasize the three core competencies of analytical thinking, biomedical understanding of the disease process, and communication. A key component of the program is its integration with the Duke medical research enterprise. Students will have the advantage of studying and working alongside medical investigators tackling real-life biomedical problems.
 

Steve Grambow Receives Award for TSHS Best Contributed Paper Award at JSM in Montreal

January 24, 2014

Steve Grambow received the Teaching of Statistics in Health Sciences (TSHS) Section's Best Contributed Paper Award for JSM 2013 for his presentation, "Doctors and Data Analysis: A Dangerous Mix?"  The presentation was part of a contributed papers session on "Biostatistical Literacy: What Medical and Public Health Professionals Need to Know about Statistics."  Steve served as the 2013 Section Chair of the TSHS a section of the American Statistical Association.  The section is devoted to excellence in teaching statistical methods and basic epidemiology and in statistical consulting within the health sciences. 
 

Paper by Susan Halabi Chosen as Cover Article in Cancer

January 15, 2014

Susan Halabi's article "Progression-Free Survival (PFS) as a Surrogate Endpoint of Overall Survival (OS) in Patients with Metastatic Renal Cell Carcinoma (mRCC)" was chosen as a featured article and placed on the cover of Cancer.  Cancer is an official journal of the American Cancer Society and reaches over 20 million people worldwide.  For more information, please see our News and Updates Section. 

Article by Raluca Gordan Chosen as One of the Top 10 Papers for 2012-2013

November 20, 2013

Raluca Gordon's recent article "Genomic regions flanking E-box binding site influence DNA binding specificity of bHLH transciption factors through DNA shale" has been selected as one of the top 10 papers in Regulatory and Systems Genomics for 2012-2013 at RECOMB/ISCB Regulatory and Systems Genomics Meeting in Toronto in November 2013.  For more information please see our News and Updates Section.
 

Brad Efron Visits B&B Department

November 12, 2013

During his visit to the Department of Biostatistics and Bioinformatics, Dr. Bradley Efron had the opportunity to share lunch with our second-year students and to attend a class on biology and communication taken by our first-year students. Much of the discussion over lunch pertained to data science as an emerging career, and what statisticians can do to prepare themselves for the role of data scientist. The class was deconstructing a manuscript describing a randomized trial, using a question and answer format. Rather like a game show, students are encouraged to answer for themselves (in fact, they are encouraged to discuss the questions beforehand within their study groups), but lifelines are available if needed. Dr. Efron provided the ultimate lifeline for the questions on bootstrapping!

First GlaxoSmithKline-Duke Statistics Workshop a Success

November 1, 2013

The first GlaxoSmithKline (GSK)-Duke Statistics Workshop on Critical Statistical Issues in Drug Development was held on October 29, 2013 at the GSK Research Triangle Park location. This is an important first step for biostatistics collaboration between GSK and Duke with the goal to exchange research progress and new ideas on critical statistical issues in clinical development. It was well attended with over 100 participants from both Duke and GSK.

Dr. Liz DeLong and Dr. Michael Pencina of the Duke Clinical Research Institute and Dr. Sara Hughes and Dr. John Whittaker, of GSK gave opening remarks. Dr. Stephen George and Dr. Kerry Lee from Duke Biostatistics and Bioinformatics presented their perspectives on design and analysis issues in drug development. Dr. Paul McSorley and Dr. Steve Novick discussed challenges and issues involved in pre/non-clinical research and data sharing for industry trials.

The GSK-Duke Statistics Workshop will be an annual event for GSK and Duke. For more information and future event details, please see the GSK-Duke Statistics website.

 Duke faculty and GSK researchers discuss statistical issues in clinical development.