Dissecting Developing and Mature Neuronal Circuit Organization Using Barcoded Transsynaptic Viral Tracing, Spatial Transcriptomics and Bioinformatics

Research in the Velmeshev lab uses single-cell genomics, spatial transcriptomic and transsynaptic viral tracing applied to human brain tissue samples, cerebral organoids, and rodent models to understand cell type-specific mechanisms of brain development and neurodevelopmental disorders such as autism. Velmeshev lab also develops bioinformatics tools for analyzing single-cell and spatial transcriptomics data.