Probing Immune Landscapes Across Scales: Insights from the Fluscape Study

Abstract: Influenza and other directly transmitted pathogens exist on a landscape that is defined by the immune status of human hosts and the contact patterns that allow the pathogen to move between those hosts. The Fluscape study, which ran between 2009-2020, was an ambitious effort to understand the immune landscape of influenza in Southern China. In this talk I will cover key results from the Fluscape study that reveal the rich and dynamics nature of the landscapes on which flu transmits, and the complex changes in immunity and behavior that drive them over a lifecourse. Bio: Justin Lessler is a faculty in the Department of Epidemiology at UNC Chapel Hill. He specializes in researching the dynamics and control of infectious disease, with particular interest in SARS-CoV-2, influenza, cholera and dengue. Justin works on the development and application of statistics, dynamic models and novel study designs to better understand and control infectious disease. Zoom: https://duke.zoom.us/j/98728618239?jst=1 Meeting ID: 987 2861 8239 This seminar series is organized by the Multiscale Immune Systems Modeling (MISM) Center of Excellence, funded by NIAID/NIH (U54AI191253).