Seminar Series

The Applied Biostatistics Seminar Series consists of a series of talks with the primary purpose of furthering statistical knowledge on an applied level. Talks will focus on advances in biostatistical methods and statistical programming techniques and their translation into addressing biomedical research questions. The seminars are open to all members of the Duke community, but primarily geared toward applied statistical researchers.

SnapHiC: a computational pipeline to identify chromatin loops from single-cell Hi-C data

Ming Hu, PhD
Friday, January 14, 2022 - 12:00 at Virtual

Abtract: Single-cell Hi-C (scHi-C) analysis has been increasingly used to map chromatin architecture in diverse tissue contexts, but computational tools to define chromatin loops at high resolution from scHi-C data are still lacking. Here, we describe Single-Nucleus Analysis Pipeline for Hi-C (SnapHiC), a method that can identify chromatin loops at...
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Introduction to Ontology in the Digital Era

Anna Maria Masci, PhD
Friday, January 14, 2022 - 01:30 at

In the digital era, most groups and organizations are dealing with a fast-growing massive amount of data in almost all knowledge domains, with biomedicine, business, and social interactions leading the way. Heterogeneity, unstructuredness, and incompleteness are relevant limitations of the current data sets, while common standards represent a powerful strategy...
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Bayesian Precision Medicine Designs for Cancer Clinical Trials

Peter F Thall, PhD
Friday, December 17, 2021 - 12:00 at Virtual

Abstract: In this talk, I will describe two Bayesian sequentially adaptive designs for oncology clinical trials that accommodate heterogeneous patients and include subgroup-specific decisions. The talk will begin with preliminary concepts on the use of utilities as criteria to quantify risk-benefit trade-offs for making decisions. The first design is for...
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Genetic Studies of Gulf War Veterans Illness

Beth Hauser, PhD
Thursday, December 9, 2021 - 12:00 at Virtual

The Genomic & Precision Medicine Forum features speakers from Duke and beyond working on innovative research in clinical, translational and basic sciences. Title - "Genetic Studies of Gulf War Veterans Illness" Elizabeth Hauser, PhD Professor, Department of Biostatistics and Bioinformatics Duke University School of Medicine Director of Computational Biology Duke...
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Systems Level Understanding and Modeling of Antimicrobial Resistance in Complex Public Health Environments: From Molecular Mechanisms to Government Policy.

Muhammad Zaman, PhD
Monday, December 6, 2021 - 12:00 at Virtual

Research in the Zaman group focuses on two over-arching themes. First, improving access to quality healthcare among vulnerable communities (refugees, internally displaced, historically oppressed and marginalized communities) both locally and globally, using a suite of multi-disciplinary approaches rootedin engineering, basic and computational sciences, social sciences and evidence based public health...
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