GCB News

Research Roundup: December 2020

Here are summaries of a selection of the papers published by GCB faculty in December 2020:

DISEASE

Doug Marchuk part of a team that investigated the effect of propranolol on the embryonic zebrafish multi-cavernous malformation and on lesion burden and hemorrhage in two murine chronic cerebral cavernous malformation models. Read more

Research Roundup: November 2020

Here are summaries of a selection of the papers published by GCB faculty in November 2020:

AGING

Restricting calories can improve the healthspan and lifespan of organisms ranging from yeast to mammals. Matt Hirschey was part of a team that used yeast to investigate how the mechanisms involved in caloric restriction could uncover future interventions for aging associated diseases. Read more

IT’S TIME TO GROW UP

Duke researchers develop new method for enhancing the maturity and functional properties of cell types derived from human stem cells.

GCB WELCOMES NEW MEMBERS

This fall, GCB welcomed two new members: Anne Yoder, Ph.D., and Purushothama Rao Tata, Ph.D.

Research Roundup: October 2020

Here are summaries of a selection of the papers published by GCB faculty in October 2020:

COVID-19

Greg Wray and team used statistical methods they developed to identify adaptive changes that arose in the SARS-CoV-2 genome in humans, but not in closely related coronaviruses found in bats and pangolins to help figure out what makes the virus so unique. Read more

Multidisciplinary University Research Initiative Tackles Synthetic Biology

Lingchong You, Ph.D., and Ashutosh Chilkoti, Ph.D., are collaborating with researchers at Washington University in St. Louis, Princeton University, and University of North Carolina on a five-year, $7.5 million Multidisciplinary University Research Initiative (MURI) award from the Department of Defense.

“For the longest time, the central dogma of biology was that structure equals function,” Chilkoti said. “But some proteins lack that structure, so they had been considered unimportant.” Research now, though, is showing that is not the case. 

GCB helps spin out success

In FY20, 17 new start-up companies formed at Duke, according to Duke’s Office of Licensing and Ventures (OLV).