GCB News

2021 Summer Scholars Program Welcomes New Recruits

The 2021 Summer Scholars Program in Genome Sciences and Medicine for Underrepresented Minority Underclassmen begins May 11 and will run through July 2.

We are welcoming eight underrepresented minority students, some who were deferred from last year’s canceled program, to work in GCB labs. These students come from Duke, North Carolina Central University, Tufts University, Agnes Scott College, and Winston Salem State University.

$8M grant aims to better understand disease mechanisms of schizophrenia

A new $8 million NIH grant seeks to uncover more clues into what genes increase the risk of developing schizophrenia.

Greg Crawford, Charlie Gersbach, Tim Reddy and Raluca Gordân have teamed up with Patrick Sullivan, Yun Li, Michael Love, and Paola Giusti-Rodriguez at UNC Chapel Hill and Flora Vaccarino at Yale University to narrow down areas of the genome previously marked relevant to schizophrenia risk.

“Schizophrenia is incredibly complex at every level,” Sullivan said, “from DNA to its clinical manifestations.”

Research Roundup: April 2021

Here are summaries of a selection of the papers published by GCB faculty in April 2021:

AGING

Using data from the Dunedin Longitudal Study, Avshalom Caspi and Terrie Moffitt were part of a team that explored possible links between one known biomarker, distributed integrity of brain white matter, and two intervention targets at midlife to explore structural brain decline and increased risk for dementia in older adults. Read more

NEW SEQUENCING INSTRUMENT PROVIDES POWERFUL RESEARCH IN SMALL PACKAGE

The Sequencing and Genomic Technologies (SGT) Core Facility has a new instrument on its bench. It might not look like much --  a small box just over a foot tall and less than a foot wide with a small door on the top and an even smaller screen on the front – but the Tapestri Platform by MissionBio is anything but weak.

A MALE BABOON'S DOMINANCE GIVES HIM BABIES, BUT COSTS HIM YEARS

Struggle for dominance leaves a mark on genes and speeds up aging

Some guys have it all: the muscle, the power, the high social status, the accelerated aging.

But wait. Faster aging? Who wants that? For male baboons, it’s the price they pay to be at the top.

RESEARCH ROUNDUP: MARCH 2021

Here are summaries of a selection of the papers published by GCB faculty in March 2021:

AGING

Terrie Moffitt, Avshalom Caspi and team used the Dunedin cohort to examine the pace of aging. By examining 19 biomarkers throughout various ages, they were able to see that some people age faster than others, putting them at higher risk for age-related illnesses earlier in life. Read more