Curriculum

The Master of Biostatistics degree, a professional degree awarded by the Duke University School of Medicine, requires 44 credits of graded course work, a Practicum experience, a Proficiency Examination, and a Master’s Project for which 6 units of credit are given.

Tracks and Timeline

There are four separate tracks in the Master of Biostatistics program. These include:

Emphasizes collaborative science and will typically include statistical electives and the application of statistical methods.

Master of Biostatistics Program Track - Clinical and Translational Research

Emphasizes computation and will typically include statistical electives and additional coursework selected from topics such as workflow best practices, software tools for large biomedical data sets, and data structures and algorithms for data-intensive applications.

Master of Biostatistics Program Track - Biomedical Data Science

Emphasizes training in advanced methods in health AI for students who already have a substantial background in data science.

Master of Biostatistics Program Track - Health AI

Emphasizes preparation for doctoral study in mathematically sophisticated programs and will typically include methodologically-oriented statistical electives and demonstrated proficiency (either in coursework or by placing out) in real analysis.

Master of Biostatistics Program Track - Mathematical Statistics

Practicum

All Master of Biostatistics students must complete a Practicum, providing hands-on experience that strengthens:

  • Analytical skills
  • Biological understanding
  • Communication abilities

Most students complete the Practicum during the summer after Year 1, but it can be scheduled in Year 2 if needed.

Proficiency Examination

Students must pass a written Proficiency Exam demonstrating mastery of core concepts from first-year courses (BIOSTAT 701–706).

  • Taken after Year 1 and before starting electives

Master's Project

A two-semester capstone (6 credits) completed in Year 2.

  • Demonstrates mastery of statistical concepts and biostatistics practice

Note: The Core foundational courses are required of all degree-seeking students. Full-time Master of Biostatistics students will select six three-credit elective courses during the second year of study.

Course Planning

First Year

26 graded coursework credit hours

Fall

Spring

BIOSTAT 701 (3) or
BIOSTAT 701A (3)

BIOSTAT 704 (3) or
BIOSTAT 704A (3) or
BIOSTAT 709 (3)

OR

BIOSTAT 724* (3)

BIOSTAT 702 (3) or
BIOSTAT 702A (3)

OR

BIOSTAT 707** (3)

BIOSTAT 705 (3) or
BIOSTAT 705A (3)

OR

BIOSTAT 826** (3)

BIOSTAT 703 (3) or
BIOSTAT 703A (3)

BIOSTAT 706 (3) or
BIOSTAT 706A (3)

BIOSTAT 703L (0)

BIOSTAT 722 (3) or
BIOSTAT 722A (3)

OR

BIOSTAT 821*** (3)

BIOSTAT 721 (3) or
BIOSTAT 721A (3)

BIOSTAT 802 (1)

BIOSTAT 801 (1)

 

Total: 13 credit hours

Total: 13 credit hours

Summer

  • Master's Proficiency Examination (Required) 
    Covers content from the first and second semesters of training.
  • Practicum (Required)
    May be completed at any point after the first year.
  • Internship (Optional)
    Students participating in a summer external internship are required to enroll in BIOSTAT 829 (1). This course is permission only.

*Students must choose 1 of these 3 courses to complete their Theory Sequence requirements. Any course not selected can be taken for elective credit in the second year with approval from the director of graduate studies.

**Required for Health AI Track to complete the Applied Data Analysis sequence. Students in other tracks may take these courses as electives in their second year with approval from the director of graduate studies.

***To meet program requirements for the Computing sequence, students must take either BIOSTAT 722/722A or BIOSTAT 821.

Second Year

Second Year (24 credit hours total)

[BIOSTAT 720 - Master’s Project and Statistical Consulting (6 credit hours) plus 18 credit hours of graded coursework]

Fall

Spring

BIOSTAT 720 (3)

+ 3 of the following:

  • BIOSTAT 707 (3)
  • BIOSTAT 710 (3)
  • BIOSTAT 713 (3)
  • BIOSTAT 719 (3)
  • BIOSTAT 732 (1-3)
  • BIOSTAT 740 (0)
  • BIOSTAT 825 (3)
  • BIOSTAT 828 (3)
  • BIOSTAT 900 (1)
  • BIOSTAT 906 (3)
  • BIOSTAT 914 (3)
  • BIOSTAT 915 (3)
  • MATH 531 (3)
  • MATH 590 (3)
  • MATH 721 (3)
  • MATH 731 (3)

 


 

BIOSTAT 720 (3)

 

+ 3 of the following:

  • BIOSTAT 708 (3)
  • BIOSTAT 709 (3)
  • BIOSTAT 718 (3)
  • BIOSTAT 724 (3)
  • BIOSTAT 725 (3)
  • BIOSTAT 732 (1-3)
  • BIOSTAT 740 (0)
  • BIOSTAT 821 (3)
  • BIOSTAT 824 (3)
  • BIOSTAT 827 (3)
  • BIOSTAT 900 (1)
  • BIOSTAT 905 (3)
  • BIOSTAT 911 (3)
  • MATH 531 (3)
  • MATH 721 (3)
  • MATH 731 (3)

*Students on the Health AI Track are required
to take BIOSTAT 827 to meet programrequirements.

Total: 3 required credit hours plus 9 elective credit hours

Total: 3 required credit hours plus 9 elective credit hours

Other Duke Departments

  • Biology: BIOLOGY 790S: Graphic Design for Biologists (3)
  • Computational Biology: Any 500 or 600 level except: 510S, 511, or 591
  • Computer Science: Any 500 or 600 level
  • Electrical and Computer Engineering: Any 500 or 600 level
  • Environmental Sciences:
    • ENVIRON 537: Environmental Health and Epidemiology (3)
    • ENVIRON 761: Geospatial Analysis for Land and Water Mgmt (3)
    • **All NSOE courses require NSOE department approval in addition to that of the student’s director of graduate study and the course instructor before submitting the NP-1 form.
  • Global Health: GLHLTH 562: Data Science and Data Visualization (3)
  • Math:
    • MATH 531: Real Analysis I (3)
    • MATH 574: Quantitative Methods for Biomedical Data (3)
    • MATH 721: Linear Algebra and Application (3)
    • MATH 731: Introduction to Real Analysis (3)
    • MATH 765: Introduction to High Dimensional Data Analysis (3)
    • MATH 766: Statistical Learning and Bayesian Nonparametrics (3)
  • Statistical Sciences:
    • Any 500 level except 501S
    • Any 600 level except 693
    • Any 700 level except 701S, 790, 791
    • Any 800 level except 851
    • Any 900 level except 993, 994, 995

First Year

[26 graded coursework credit hours]

Fall

Spring

Summer

BIOSTAT 701 (3) or
BIOSTAT 701A (3)

BIOSTAT 704 (3) or
BIOSTAT 704A (3) 
or
BIOSTAT 709 (3)

Master’s Proficiency Examination
(covers content from  BIOSTAT 701-706)

Practicum (may be completed at
any point after the first
year)

BIOSTAT 702 (3) or
BIOSTAT 702A (3)

BIOSTAT 705 (3) or
BIOSTAT 705A (3)

 

BIOSTAT 703 (3) or
BIOSTAT 703A (3)

BIOSTAT 706 (3) or
BIOSTAT 706A (3)

 

BIOSTAT 703L (0)

BIOSTAT 722 (3) or
BIOSTAT 722A (3) 
or
BIOSTAT 821 (3)

 

BIOSTAT 721 (3) or
BIOSTAT 721A (3)

BIOSTAT 802 (1)

 

BIOSTAT 801 (1)

 

 

Total: 13 credit hours

Total: 13 credit hours

 

 

Second Year

[24 credit hours – Master’s project (6) plus graded coursework credit hours (18)]

Fall

Spring

BIOSTAT 720 (3)

BIOSTAT 720 (3)


+ 3 of the following:
  • BIOSTAT 707 (3)
  • BIOSTAT 710 (3)
  • BIOSTAT 713 (3)
  • BIOSTAT 719 (3)
  • BIOSTAT 732 (1-3)
  • BIOSTAT 740 (0)
  • BIOSTAT 823 (3)
  • BIOSTAT 825 (3)
  • BIOSTAT 900 (1)
  • BIOSTAT 906 (3)
  • BIOSTAT 914 (3)
  • BIOSTAT 915 (3)
  • MATH 531 (3)
  • MATH 590 (3)
  • MATH 721 (3)
  • MATH 731 (3) 

 + 3 of the following:

  • BIOSTAT 708 (3)
  • BIOSTAT 709 (3)
  • BIOSTAT 718 (3)
  • BIOSTAT 724 (3)
  • BIOSTAT 725 (3)
  • BIOSTAT 732 (1-3)
  • BIOSTAT 740 (0)
  • BIOSTAT 821 (3)
  • BIOSTAT 824 (3)
  • BIOSTAT 900 (1)
  • BIOSTAT 905 (3)
  • BIOSTAT 911 (3)
  • MATH 531 (3)
  • MATH 721 (3)
  • MATH 731 (3)

Biology (3):

BIOLOGY 790S

Computational Biology (3):

Any 500 and 600 level except

510S, 511, or 591

Computer Science (3):

Any 500 and 600 level

Environmental (3):

ENVIRON 537

Global Health (3):

Global Health 562

Statistical Science (3):

Any 500 level except 501s

Any 600 level except for 693

Any 700 level except for 701S, 790, 791.

Any 800 level except for 851

Any 900 level except for 993, 994,

and 995

Biology (3):

BIOLOGY 790S

Computational Biology (3):

Any 500 and 600 level except

510S, 511, or 591

Computer Science (3):

Any 500 and 600 level

Environmental (3):

ENVIRON 537

Global Health (3):

Global Health 562

Statistical Science (3):

Any 500 level except 501s

Any 600 level except for 693

Any 700 level except for 701S, 790, 791.

Any 800 level except for 851

Any 900 level except for 993,

994, and 995

Total: 3 required credit hours  plus 9 elective credit hours

Total: 3 required credit hours  plus 9 elective credit hours

 

Policy for Substitution of Core Course Requirements

Students who have relevant pre-matriculation coursework or training may request to meet the core course requirements for the first year Statistical Theory and Computing course sequences by taking more advanced graduate-level courses in related areas for equivalent credit. Advanced courses that may be selected are: BIOSTAT 732 (3 credits), BIOSTAT 828, BIOSTAT 906, STA 532, STA 640, STA 732, and ECE 551D. Testing or other evaluation may be required prior to approval. Instructor permission may be required for enrollment in some courses. Requests must be submitted to the Director of Graduate Studies either 2 weeks prior to the start of the fall semester (for courses to be taken in the fall) or no later than the last day of the fall semester (for courses to be taken in the spring). Approval is required from the Director of Graduate Studies.